Our proprietary, injectable extended-release technology allows us to encapsulate small molecules, peptides and proteins in microspheres made of biodegradable polymers. With extended-release profiles lasting from days to months, these microspheres are designed to eliminate the need for frequent dosing and may be used for either subcutaneous or intramuscular delivery. We have two commercial products based on our extended-release technology.
The Alkermes extended-release technology is distinguished by:
- Clinically proven extended-release of medication from micospheres in human clinical trials.
- Demonstrated safety and tolerability in human clinical trials.
- Potential to improve patient adherence, especially where extended-release dosage administration is an important factor for the selection of a medication for treatment.
- Broad applicability to small molecules, peptides and proteins.
- Demonstrated manufacturing capability at laboratory scale, pilot scale and commercial manufacturing scale, with strict adherence to cGMPs.
- Ability to achieve a customized extended-release profile lasting from days to months.